CDF to consider once-a-day pill for ovarian cancer

NICE has invited biopharmaceutical company Tesaro to submit a proposal for including niraparib in the Cancer Drugs Fund (CDF), for treating some types of recurrent ovarian cancer.

According to company estimates, up to 850 women in England and Wales could benefit from this new treatment with late diagnosis often leaving women with this type of cancer with chemotherapy as the only available treatment. Ovarian cancer is one of the most common types of cancer in women.

Niraparib was appraised for the treatment of women with relapsed ovarian, fallopian tube and peritoneal cancer who have had two or more courses of platinum based chemotherapy. Trails have shown that the drug stalled cancer growth by around six to 15.5 months more than placebo, depending on a woman’s genetic profile.

Mirella Marlow, acting director of the centre for health technology evaluation at NICE said: “The outcome for women with ovarian cancer is generally poor, with less than 35 per cent surviving for five years after diagnosis. The inclusion of niraparib in the Cancer Drugs Fund will give women early access to this treatment while uncertainties in the clinical evidence can be addressed through the collection of additional data.”

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This story was first published in digitalhealth.net

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