Painkillers linked to heart failure risk in elderly, study suggests

A study published in the British Medical Journal has found that taking non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen and diclofenac may carry an increased risk of heart failure for over-65s.

The research involved examining data on 10 million people from the UK, the Netherlands, Italy and Germany, aged 77 on average who consumed the painkillers.

While the findings showed there was little relevance for most under-65s, it suggested there was a possible concern for elderly patients, where taking NSAIDs increased the risk of being admitted to hospital with heart failure by 19 per cent.

In an interview with the BBC, Helen Williams, consultant pharmacist for cardiovascular disease at the Royal Pharmaceutical Society, explained: "Hypertension, diabetes, maybe kidney problems - it's in those patients when we add these drugs on top that there might be a small increase in their risk.

"If you take a very occasional course - it's like most people will do for aches and pains, sports injuries etcetera - then there's no need to worry."

She added: "I think I would say if you're a young person who is regularly going to buy these drugs, and effectively taking them all the time, you probably should be supervised by a clinician because there are other issues with these drugs and we might want to keep an eye, for example, on your kidneys."

Prof Peter Weissberg, medical director at the BHF, said: "This large observational study reinforces previous research showing that some NSAIDs, a group of drugs commonly taken by patients with joint problems, increase the risk of developing heart failure.

"It has been known for some years now that such drugs need to be used with caution in patients with, or at high risk of, heart disease.

"This applies mostly to those who take them on a daily basis rather than only occasionally.

"Since heart and joint problems often coexist, particularly in the elderly, this study serves as a reminder to doctors to consider carefully how they prescribe NSAIDs, and to patients that they should only take the lowest effective dose for the shortest possible time.

"They should discuss their treatment with their GP if they have any concerns."

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This story was first published in digitalhealth.net

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