New vaccine to help prevent heart disease

Trials of a cholesterol-lowering vaccine to help prevent heart disease are under way in humans after successful studies in mice.

Researchers are testing the safety of their experimental treatment in 72 volunteers at the Medical University of Vienna.

The vaccine aims to stop fatty deposits from clogging the arteries by helping the body’s immune system attack a protein that would otherwise let ‘bad’ low density lipoprotein cholesterol to build up in the bloodstream. It would offer an alternative to patients who take pills daily to cut their risk of stroke, angina and heart attacks.

Dr Guenther Staffler and colleagues from The Netherlands Organisation of Applied Scientific Research say that it will take years more of testing to know if the treatment will be safe and effective enough for human use in the European Heart Journal. They predict that patients could have a yearly booster shot to maintain their immunity.

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This story was first published in digitalhealth.net

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